Both are full-size wireless keyboard-and-mouse sets with number pads and straightforward receiver-based connections for fixed desks. The MK295 listing specifies Windows setup and an ambidextrous compact mouse, while the MK345 uses one USB-A nano receiver for both devices and requires USB-A or an adapter.
The deciding difference is desk comfort: choose the MK295 for quieter typing and clicking or for left- and right-handed mouse use; choose the MK345 for its integrated palm rest and compact right-handed mouse.

Logitech MK295 Silent Wireless Keyboard and Mouse Combo (Graphite)
Best for Best for quiet offices and calls
A practical full-size wireless keyboard and compact mouse for shared offices, calls, and home desks where quieter clicks matter more than advanced controls.
- + Quieter keys and mouse clicks than typical basic desktop sets
- + Full-size keyboard includes a dedicated number pad
- + Simple receiver-based Windows setup
- − No Bluetooth or multi-device switching
- − Compact mouse may feel cramped in larger hands
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Logitech MK345 Wireless Keyboard and Mouse Combo
Best for Best for a complete desk refresh
A practical full-size keyboard and compact right-handed mouse that share one USB-A receiver. Best for fixed office desks that favor simplicity over advanced features.
- + Full-size keyboard includes a dedicated number pad
- + Keyboard and mouse share one USB-A nano receiver
- + Integrated palm rest supports everyday desk use
- − No stated Bluetooth connection for multi-device switching
- − Compact right-handed mouse may not suit large hands or left-handed users
Full review